Holding it down in southwest Worcester (say it with us… Wuh-Stuh), smack dab in the center of Massachusetts, you’ll find a low-key plug for high-grade weed at Mayflower, a connoisseur-grade cannabis dispensary located at 645 Park Avenue.
Sharing a large parking lot with Advanced Auto and a local bank, this well-branded spot sits in its own mini Emerald Triangle between Park Ave, Mill Street, and Main Street. Easy to get to, easy to park, and very accessible and welcoming for all to enter using the entry steps or ramp.
We call it “low-key” because the entrance to the shop almost resembles an old school speakeasy. But you don’t need to know a secret password to enter, you just need to be of legal age and be curious about cannabis. From beginners to seasoned heads, everyone who steps inside discovers that Mayflower has the knowledge and the consumption options to pair you with something you will love.
The interior of the Mayflower Worcester location is a reflection of the working-class community that it serves. No flash or glitter here, but it’s not ‘strictly business’ either. The staff at Mayflower in Worcester is second-to-none when it comes to passion for the plant and for putting people on the path to an amazing cannabis experience.
Their job is made a bit easier by the depth and levels of consumption options, price points, deals, and dank that you will find on their full spectrum menu either online or in-store. The Commonwealth’s finest flower, pre-rolls, edibles, concentrates, vape carts, tinctures, topicals, and more are all found at Mayflower Worcester.
For those who are seeking top-shelf cannabis wellness products, we can say firsthand that Mayflower is your source for award-winning Beard Bros Pharms wellness cannabis products – ask your budtender about them next time you visit!
It is an honor to have our homegrown legacy brand on the top shelf in Worcester along with other high-demand operators like Sanctuary Medicinals, Wee-De, Shaka, Nova Farms, and more Mayflower crowd favorites.
“Nestled on Park Avenue, our Worcester dispensary provides a welcoming environment for everyone, from recreational users to medical patients. Discover top-quality cannabis from in-house and local Massachusetts brands, along with best-in-class service from our knowledgeable staff. Join our loyalty program for rewards, and enjoy the convenience of online ordering with options for pickup or delivery.”
The team at Mayflower has put together some dope daily and recurring deals, and a generous AF rewards program, but you don’t have to take our word for it–let’s have a look at what some Worcester weed fans have to say about this joint.
“Marcy was fantastic and extremely knowledgeable and the products are great as well! Love the whole team at Mayflower Worcester!” – 5-Star Google review from April 2025 by guest Derik F.
“Asia helped me out! Very knowledgeable and funny. Helped me with what I was looking for and with good service.” – 5-Star Google review from May 2025 by guest Asap L.
“Prices are great. Staff is awesome. And I love the text updates. Ashlyn, Ashley, Marcy and Marissa are all fantastic. They make it worth the visit. Rest of the staff is also attentive and nice.” – 5-Star Google review from May 2025 by guest Kim H.
We love how hundreds of happy reviews call out specific Mayflower Worcester team members for their great service. Whether you want to order online and have a quick re-up experience, or if you like to linger a little longer in the shop, Mayflower welcomes all weed-lovers with open arms, amazing cannabis, and great deals.
Mayflower Dispensary in Worcester, Massachusetts Has the Best Cannabis in the Commonwealth
From their inspirational Positive Impact Plan, to their Mayflower Artist Spotlight Series (M.A.S.S.), to their Fellowship Program, Community Gardens, and Skills Seminars, Mayflower cannabis dispensary in Lowell is committed to their community, and it shows.
When you buy Beard Bros Pharms products from Mayflower cannabis dispensaries you support us, you support them, and you support the surrounding community. That gets me high just thinking about it!
Speaking of community, almost directly across Park Avenue from Mayflower is one of the most badass head shops in the entire country, if not the entire world–Lili’s Glass. IYKYK but if you don’t know, this spot is a mecca for heady glass collectors featuring work from the best of the best… kind of like Mayflower!
645 Park Ave., Worcester, MA 01603
Hours: Mon-Sat 11am-9pm / Sunday 11am-7pmWebsite: Mayflower | Worcester Location
Deals: Daily Deals, Discounts, MVP Rewards & more!
Nearby Munchies: Alright I’ll tell ya what I would do, and have done. I’d score some good stuff over at Mayflower, then I’d go right across the street to friggin’ Applebee’s and I’d inhale a friggin’ Quesadilla Burger and I would absolutely regret it later in the day. But that’s later in the day! Live in the moment! Inhale the burger!
