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Cannabinoids Work Better Together To Combat Pain

cannabinoids work better together combat pain

The mounting research on cannabis and its pain-relieving qualities is undeniable – but is there a space in the market for an in-depth analysis of how cannabinoids can be combined to improve the results drastically? On their own, cannabinoids can target various health problems – combining them can be the key to developing highly efficient products that can service a wide variety of patients suffering from severe daily pain. Let’s take an in-depth look at how cannabinoids can potentially be combined to combat pain.

Targeting Pain – The Radicle Science Trial  

CBD has been the frontrunner for pain relief – known for relief without the psychedelic high. CBD influences the body to use its endocannabinoids more efficiently. This does not directly affect the system like THC, for example, and does not impair function. When using CBD, the body’s anandamide levels are increased, reducing pain perception. Inflammation in the body is also targeted, helping with pain relief. These qualities have made CBD the main ingredient in manufacturing pain-relieving products, but new research indicates that combining CBD with other cannabinoids can improve pain management. CBG and CBC are two components we can look at that might make a powerful compound.

Radicle Science and Open Book Extracts have joined forces on a clinical trial focusing on pain and CBD. They delivered a mix of CBD compounds, all containing a certain amount of CBD and some containing added cannabinoids. Here are some of the key takeaways from the study:

  • 1629 sufferers took the compounds for a month.
  • 44.8% of the sufferers who took any of the compounds experienced relief.
  • The addition of 20mg CBS to 40mg CBD improved the pain relief significantly.
  • Radicle Science and OBX will continue their partnership and endeavour to study the results with even more cannabinoids, for example, THCV, CBN and CBG.

These studies are paramount to our understanding of how cannabinoids influence the pain system. This in turn can affect the manufacturing of products that can deliver better results. How can we best describe this relationship and interaction between cannabinoids? Synergy:

“the interaction or cooperation of two or more organizations, substances, or other agents to produce a combined effect greater than the sum of their separate effects”

Synergy can be the future of cannabinoid products – combining the best features of each strain to develop potent effects.

Cannabinoids Work Better Together To Combat Pain

The Different Shapes Of CBD Products

The wide gap in the industry for sustainable pain relief has links to cancer patients, people living with epilepsy, neurological pain effects, PTSD, and a host of other areas of concern. These patients can also vary in their need for pain relief and the shape of their products. The most common forms of CBD products are:

  • Oils
  • Gummies
  • Capsules
  • Creams
  • Patches

The profound effect of these products on pain has been well-documented in studies – but the results of the Radicle Science study have shown that these products can be even more finely tuned with the combination of cannabinoids to create a wider targeting product. This also opens the doors for cultivators, manufacturers and sellers to develop new strategies to adapt to the growing market needs. This also places the patient in the centre of their treatment- allowing them to choose and tailor products to their personal needs.

Combat Pain


The continuous efforts of research trials are vital to further investigate the interaction of various cannabinoids. The trial results thus far allow in-depth insight into how synergy can be used to achieve higher levels of pain relief. The combination of cannabinoids can lead to the production of better products – and reach a wider range of sufferers. This can be implemented into the cultivation, manufacturing and distribution levels of the cannabis market.

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